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White Turmeric (Kaempferia rotunda L.) extract liquid soap preparation for feminine hygiene and effectiveness against Candida albicans



Abstract
Background: Kaempferia rotunda L. (white turmeric) contains alkaloids, phenols, saponins,
glycosides, steroids, terpenoids, and other ingredients with antimicrobial, anticancer, antiallergic,
antioxidant, analgesic, and antifungal properties. Meanwhile, vaginal discharge or fluor albus is
an excessive release of non-bloody fluid caused by the Candida albicans fungus. Objective: This
study aimed to formulate white turmeric extracts (Kaempferia rotunda L.) into standard liquid
soap for feminine hygiene and to determine the level of antifungal activity against Candida
albicans. Methods: The liquid soap was produced by the maceration of white turmeric in 70%
ethanol, which was evaporated until a thick extract was formed. This soap preparation included
7% stearic acid, 1% adeps lanae, 2% triethanolamine (TEA), 5% glycerol, white turmeric extract
(at concentrations of 20%, 25%, and 30%), vanilla oil, and distilled water added up to 100 mL.
Furthermore, the well method was used to test the antifungal activity of the preparations, and
analysis was done on SPSS. Results: The results showed that the white turmeric ethanol extract
was effective against the Candida albicans fungus at concentrations of 25% and 30%, with
inhibitory diameters of 11 mm and 15 mm (categorised as powerful), respectively. Also, the liquid
soap preparations of the extract revealed antifungal activity at a concentration of 30%, with a 9.6
mm inhibition diameter (medium category). The soap met Indonesian National Standard (SNI)
requirements, including organoleptic, pH, high foam, and viscosity properties. Conclusion: The
white turmeric ethanol extract can be formulated into a feminine hygiene soap with antifungal
activity at a concentration of 30%


Ketersediaan

P016P016RAK UMUMTersedia

Informasi Detil

Judul Seri
-
No. Panggil
P016
Penerbit International Pharmaceutical Federation (FIP) : .,
Deskripsi Fisik
-
Bahasa
English
ISBN/ISSN
-
Klasifikasi
P016
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
2022
Subyek
Info Detil Spesifik
-
Pernyataan Tanggungjawab

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